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Wakefield, Devin L., David Holowka and Barbara Baird: The FcεRI Signaling Cascade and Integrin Trafficking Converge at Patterned Ligand Surfaces.  Mol. Biol. Cell (2017). (DOI)

Korzeniowski, Marek K., Eva Wisniewski, Barbara Baird, David Holowka and Tamas Balla: Molecular anatomy of the early events in STIM1 activation; oligomerization or conformational change ?  J. Cell Sci. 130(17): 2821-2832. (DOI)

Holowka, D. and B. Baird: Mechanisms of epidermal growth factor receptor signaling as characterized by patterned ligand activation and mutational analysis.  Biochimica et Biophysica Acta 1859(Issue 9, Part A): 1430-1435 (2017). (DOI)

Sun, C., D.A. Holowka, B.A. Baird and W.R. Dichtel: Beyond Media Composition: Cell Plasma Membrane Disruptions by Graphene Oxide.  Chem 2(3): 324-325 (2017). (DOI)

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Shelby, S.A., S.L. Veatch, D.A. Holowka and B.A. Baird: Functional nanoscale coupling of Lyn kinase with IgE-FcεRI is restricted by the actin cytoskeleton in early antigen-stimulated signaling. Mol. Biol. Cell 27(22): 3645-3658 (2016). (DOI)

Sun, C., D.L. Wakefield, Y. Han, D.A. Muller, D.A. Holowka, B.A. Baird and W.R. Dichtel: Graphene Oxide Nanosheets Stimulate Ruffling and Shedding of Mammalian Cell Plasma Membranes. Chem 1(2): 273-286 (2016). (DOI)

Wilson, J.D., S.A. Shelby, D. Holowka and B. Baird: Rab11 Regulates the Mast Cell Exocytic Response.  Traffic 17(9), 1027-1041 (2016). (DOI)

Holowka, D. and B. Baird: Roles for lipid heterogeneity in immunoreceptor signaling.  Biochimica et Biophysica Acta 1861(8), 830-836 (2016). (DOI)

Korzeniowski, M.K., B. Baird and D. Holowka: STIM1 activation is regulated by a 14 amino acid sequence adjacent to the CRAC activation domain.  AIMS Biophysics 3(1), 99-118 (2016). (DOI)

Holowka, D., M. Wilkes, C. Stefan and B. Baird: Roles for Ca2+ mobilization and its regulation in mast cell functions:  recent progress.  Biochem. Soc. Trans. 44(2), 505-509 (2016). (DOI)

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Jayant, K., A. Singhai, Y. Cao, J.B. Phelps, M. LIndau, D.A. Holowka, B.A. Baird and E.C. Kan: Non-Faradaic Electrochemical Detection of Exocytosis from Mast and Chromaffin Cells Using Floating-Gate MOS Transistors.  Scientific Reports 5, 18477 (2015). (DOI)

Bryant, K.L., B. Baird and D. Holowka: A Novel Fluorescence-based Biosynthetic Trafficking Method Provides Pharmacologic Evidence that Pl4-Kinase IIIalpha is Important for Protein Trafficking from the Endoplasmic Reticulum to the Plasma Membrane.  BMC Cell Biology 16(5), 1-26 (2015). (DOI)

Holowka, D. and B. Baird:  Nanodomains in Early and Later Phases of FcεRI Signaling.  Essays in Biochemistry: Membrane Nanodomains, Vol. 57, 147-163 (2015). (DOI)

Cohen, R., D. Holowka and B. Baird:  Real-time imaging of Ca2+ mobilization and degranulation in mast cells.  Methods in Molecular Biology 1220 (Mast Cells: Methods and Protocols, 2nd ed.), Part IV, Ch. 22, pp. 347-363 (2015). (DOI)

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Singhai, A., D.L. Wakefield, K.L. Bryant, S.R. Hammes, D. Holowka and B. Baird:  Spatially Defined EFG Receptor Activation Reveals an F-Actin-Dependent Phospho-Erk Signaling Complex.  Biophys. J. 107(11), 2639-2651 (2014). (DOI)

Kelly, C.V., D.L. Wakefield, D.A. Holowka, H.G. Craighead and B.A. Baird:  Near-Field Fluorescence Cross-Correlation Spectroscopy on Planar Membrane.  ACS Nano 8(7), 7392-7404 (2014). (DOI)

Wilkes, M.M., J.D. Wilson, B. Baird and D. Holowka:  Activation of Cdc42 is Necessary for Sustained Oscillations of Ca2+ and PIP2 Stimulated by Antigen in RBL Mast Cells.  Biology Open 3(8), 700-710  (2014). (DOI)

Holowka, D., M.K. Korzeniowski, K.L. Bryant and B. Baird:  Polyunsaturated fatty acids inhibit stimulated coupling between the ER Ca2+ sensor STIM1 and the Ca2+ channel protein Orai1 in a process that correlates with inhibition of stimulated STIM1 oligomerization.  Biochim. Biophys. Acta 1841(8): 1210-1216 (2014). (DOI)

Chylek, L.A., D.A. Holowka, B.A. Baird and W.S. Hlavacek:  An interaction library for the FcεRI signaling network.  Front. Immunol. 5: 172 (2014). (DOI)

Olubi, O., D. Gadi, B. Sannigrahi, M. Williams, B. Baird and I. Khan:  Fabrication of electroactive composite nanofibers of functionalized polymer and CNT capable of specifically binding with the IgE (Immunoglobulin E) antibody.  Surf. Interface Anal. 46(4): 237-242 (2014). (DOI)

Welch, M.E., N.L. Ritzert, H. Chen, N.L. Smith, M.E. Tague, Y. Xu, B.A. Baird, H.D. Abruña and C.K. Ober: Generalized Platform for Antibody Detection using the Antibody Catalyzed Water Oxidation Pathway.  J. Am. Chem. Soc. 136(5): 1879-1883, 2014. (DOI)

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Shelby, S.A., D. Holowka, B. Baird and S.L. Veatch:  Distinct Stages of Stimulated FcεRI Receptor Clustering and Immobilization Are Identified through Superresolution Imaging.  Biophys. J. 105(10): 2343-2354, 2013. (DOI)

Bryant, K.L., M.A. Antonyak, R.A. Cerione, B. Baird and D. Holowka:  Mutations in the Polybasic Juxtamembrane Sequence of Both Plasma Membrane- and Endoplasmic Reticulum-localized Epidermal Growth Factor Receptors Confer Ligand-independent Cell Transformation.  J. Biol. Chem. 288(48): 34930-34942, 2013. (DOI)

Smith, N.L., D.S. Abi Abdallah, B.A. Butcher, E.Y. Denkers, B. Baird and D. Holowka:  Toxoplasma gondii Inhibits Mast Cell Degranulation by Suppressing Phospholipase Cg–mediated Ca2+ Mobilization.  Front. Microbiol. 4: 179, 2013. (DOI)

Midthun, K.M., P.G. Taylor, C. Newby, M. Chatzichristidi, P.S. Petrou, J.-K. Lee, S.E. Kakabakos, B.A. Baird and C.K. Ober:  Orthogonal Patterning of Multiple Biomolecules Using an Organic Fluorinated Resist and Imprint Lithography.  Biomacromolecules 14(4): 993-1002, 2013. (DOI)

Santos, M.deS., R.M.Z.G. Naal, B. Baird and D. Holowka: Inhibitors of PI(4,5)P2 Synthesis Reveal Dynamic Regulation of IgE Receptor Signaling by Phosphoinositides in RBL Mast Cells.  Mol. Pharmacol. 83(4): 793-804, 2013. (DOI)

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Doss, J., O. Olubi, B. Sannigrahi, M.D. Williams, D. Gadi, B. Baird and I. Khan:  Procedure for Fabricating Biofunctional Nanofibers.  J. Vis. Exp. 67: e4135, 2012. (DOI)

Welch, M. Elizabeth, Y. Xu, H. Chen, N. Smith, M.E. Tague, H.D. Abruña, B. Baird and C.K. Ober: Polymer Brushes as Functional, Patterned Surfaces for Nanobiotechnology.  J. Photopolym. Sci. Technol. 25(1): 53-56, 2012. (DOI)

Lee, J., S.L. Veatch, B. Baird and D. Holowka: Molecular Mechanisms of Spontaneous and Directed Mast Cell Motility.  J. Leukoc. Biol. 92(5): 1029-1041, 2012. (DOI)

Holowka, D., N. Calloway, R. Cohen, D. Gadi, J. Lee, N.L. Smith and B. Baird: Roles for Ca2+ Mobilization and its Regulation in Mast Cell Functions.  Front. Immunol. 3: 104, 2012. (DOI)

Reuven, D., D. Sil, B. Sannigrahi, X-Q Wang, B. Baird and I.M. Khan: Archetypical Conductive Polymer Structure for Specific Interaction with Proteins.  J. Macromol. Sci. (Part A: Pure & Appl. Chem.) 49(4): 330-338, 2012. (DOI)

Veatch, S., E. Chiang, P. Sengupta, D. Holowka and B. Baird: Quantitative Nano-Scale Analysis of IgE-FcεRI Clustering and Coupling to Early Signaling Proteins.  J. Phys. Chem. B 116(23): 6923-6935, 2012. (DOI)

Veatch, S.L., B.B. Machta, S.A. Shelby, E.N. Chiang, D.A. Holowka and B.A. Baird: Correlation Functions Quantify Super-resolution Images and Estimate Apparent Clustering Due to Over-counting.  PLoS One 7(2): e31457, 2012. (DOI)

Cohen, R., K. Corwith, D. Holowka and B. Baird: Spatiotemporal Resolution of Mast Cell Granule Exocytosis Reveals Correlation with Ca2+ Wave Initiation.  J. Cell Sci. 25(12): 2986-2994, 2012. (DOI)

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Gadi, D., A. Wagenknecht-Wiesner, D. Holowka and B. Baird: Sequestration of Phosphoinositides by Mutated MARCKS Effector Domain Inhibits Stimulated Ca2+ Mobilization and Degranulation in Mast Cells.  Mol. Biol. Cell 22(24): 4908-4917, 2011. (DOI)

Chiang, Y-W, A.J. Costa-Filho, B.A. Baird and J.H. Freed: 2D-ELDOR Study of Heterogeneity and Domain Structure Changes in Plasma Membrane Vesicles Upon Crosslinking of IgE Receptors.  J. Phys. Chem. B 115(35): 10462-10469, 2011. (DOI)

Calloway, N., T. Owens, K. Corwith, W. Rodgers, D. Holowka and B. Baird: Stimulated Association of STIM1 and Orai1 is Regulated by the Balance of PtdIns(4,5)P2 between Distinct Membrane Pools.  J. Cell Sci. 124(15): 2602-2610, 2011. (DOI)

Torres, A.J., D. Holowka and B.A. Baird: Micropatterned Ligand Arrays to Study Spatial Regulation in Fc Receptor Signaling. In Methods in Molecular Biology, Vol. 748 (Immune Receptors: Methods and Protocols, Eds., J.P. Rast and J.W.D. Booth), Chap. 14, pp. 195-207, 2011.

Chiang, E.N., R. Dong, C.K. Ober and B.A. Baird: Cellular Responses to Patterned Poly(acrylic acid) Brushes.  Langmuir 27(11): 7016-7023, 2011. (DOI)

Kelly, C.V., B.A. Baird and H.G. Craighead: An Array of Planar Apertures for Near-Field Fluorescence Correlation Spectroscopy.  Biophys. J. 100(7): L34-L36, 2011. (DOI)

Brust-Mascher, I., B.A. Baird and W.W. Webb: Response to Kang et al.  Biophys. J. 100(3): 793-794, 2011. (DOI)

Suteewong, T., H. Sai, R. Cohen, S. Wang, M. Bradbury, B. Baird, S. Gruner and U. Wiesner: Highly Aminated Mesoporous Silica Nanoparticles with Cubic Pore Structure.  J. Am. Chem. Soc. 133(2): 172-175, 2011. (DOI)

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Smith, N.L., S. Hammond, D. Gadi, A. Wagenknecht-Wiesner, B. Baird and D. Holowka: Sphingosine derivatives inhibit cell signaling by electrostatically neutralizing polyphosphoinositides at the plasma membrane.  Self/Nonself 1(2): 133-143, 2010. (DOI)

Calloway, N., D. Holowka and B. Baird: A Basic Sequence in STIM1 Promotes Ca2+ Influx by Interacting with the C-Terminal Acidic Coiled-Coil of Orai1.  Biochemistry 49(6): 1067-1071, 2010. (DOI)

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Cohen, R., A. Torres, H-T Ma, D. Holowka and B. Baird: Ca2+ Waves Initiate Antigen-Stimulated Ca2+ Responses in Mast Cells.  J. Immunol. 183(10): 6478-6488, 2009. (DOI)

Haka, A.S., I. Grosheva, E. Chiang, A.R. Buxbaum, B.A. Baird, L.M. Pierini and F.R. Maxfield: Macrophages Create an Acidic Extracellular Hydrolytic Compartment to Digest Aggregated Lipoproteins.  Mol. Biol. Cell 20(23): 4932-4940, 2009. (DOI)

Rastogi, A., S. Nad, M. Tanaka, N. Da Mota, M. Tague, B.A. Baird, H.D. Abruña and C.K. Ober: Preventing Non-Specific Adsorption on Polymer Brush Covered Gold Electrodes Using a Modified ATRP Initiator.  Biomacromolecules 10(10): 2750-2758, 2009. (DOI)

Han, X., N.L. Smith, D. Sil, D.A. Holowka, F.W. McLafferty and B.A. Baird: IgE Receptor-Mediated Alteration of Membrane-Cytoskeleton Interactions Revealed by Mass Spectrometric Analysis of Detergent-Resistant Membranes.  Biochemistry 48(27): 6540-6550, 2009. (DOI)

Hammond, S., A. Wagenknecht-Wiesner, S.L. Veatch, D. Holowka and B. Baird: Roles for SH2 and SH3 domains in Lyn kinase association with activated FcεRI in RBL mast cells revealed by patterned surface analysis.  J. Struct. Biol. 168(1): 161-167, 2009. (DOI)

Vasudevan, L., A. Jeromin, L. Volpicelli-Daley, P. De Camilli, D. Holowka and B. Baird: The β- and γ-isoforms of type I PIP5K regulate distinct stages of Ca2+ signaling in mast cells.  J. Cell Sci. 122(14): 2567-2574, 2009. (DOI)

Hammond, S., D. Holowka and B. Baird. Membrane Compartments Related to Signaling and Trafficking in Immune Cells. In Wiley Encyclopedia of Chemical Biology, 4 Volume Set (Ed. T.P. Begley) Wiley InterScience; Vol. 2, pp. 718-728, January 2009.

Calloway, N., M. Vig, J.-P. Kinet, D. Holowka and B. Baird: Molecular Clustering of STIM1 with Orai1/CRACM1 at the Plasma Membrane Depends Dynamically on Depletion of Ca2+ Stores and on Electrostatic Interactions.  Mol. Biol. Cell 20(1): 389-399, 2009. (DOI)

Holowka, D.: Biomembrane liquid-liquid phase separation and detergent resistance: a relationship strengthened.  Biochem. J. 424: e5-6, 2009.

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Torres, A.J., L. Vasudevan, D. Holowka and B. Baird: Focal Adhesion Proteins Connect IgE Receptors to the Cytoskeleton as Revealed by Micropatterned Ligand Arrays.  Proc. Natl. Acad. Sci. 105(45): 17238-17244, 2008. (DOI)

Sannigrahi, B., D. Sil, B. Baird, X.Q. Wang and I.M. Khan. Synthesis and Characterization of α,ω-bi[2,4-dinitrophenyl (DNP)] poly(2-methoxystyrene) Functional Polymers. Initial Evaluation of the Interaction of the Functional Polymers with RBL Mast Cells.  J. Macromol. Sci. (Part A: Pure & Appl. Chem.) 45(8): 664-671, 2008. (DOI)

Veatch, S., P. Cicuta, P. Sengupta, A. Honerkamp-Smith, D. Holowka and B. Baird: Critical Fluctuations in Plasma Membrane Vesicles.  ACS Chem. Biol. 3(5): 287-293, 2008. (DOI)

Torres, A.J., M. Wu, D. Holowka and B. Baird: Nanobiotechnology and Cell Biology: Micro- and Nanofabricated Surfaces to Investigate Receptor-Mediated Signaling.  Annu. Rev. Biophys. 37: 265-288, 2008. (DOI)

Sengupta, P., A. Hammond, D. Holowka and B. Baird: Structural determinants for partitioning of lipids and proteins between coexisting fluid phases in giant plasma membrane vesicles.  Biochim. Biophys. Acta 1778(1): 20-32, 2008. (DOI)

Das, R., E. Baird, S. Allen, B. Baird, D. Holowka and B. Goldstein: Binding Mechanisms of PEGylated Ligands Reveal Multiple Effects of the PEG Scaffold.  Biochemistry 47(3): 1017-1030, 2008. (DOI)

Das, R., S. Hammond, D. Holowka and B. Baird: Real-Time Cross-Correlation Image Analysis of Early Events in IgE Receptor Signaling.  Biophys. J. 94(12): 4996-5008, 2008. (DOI)

Curtis, T., R.M. Naal, C. Batt, J. Tabb and D. Holowka: Development of a mast cell-based biosensor. Biosens. Bioelectron. 23: 1024-1031, 2008.

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Sengupta, P., B. Baird and D. Holowka: Lipid rafts, fluid/fluid phase separation, and their relevance to plasma membrane structure and function.  Semin. Cell & Dev. Biol. 18(5): 583-590, 2007. (DOI)

Dong, R., S. Krishnan, B.A. Baird, M. Lindau and C.K. Ober: Patterned Biofunctional Poly(acrylic acid) Brushes on Silicon Surfaces.  Biomacromolecules 8(10): 3082-3092, 2007. (DOI)

Sil, D., J.B. Lee, D. Luo, D. Holowka and B. Baird: Trivalent Ligands with Rigid DNA Spacers Reveal Structural Signaling in RBL Mast Cells.  ACS Chem. Biol. 2(10): 674-684, 2007. (DOI)

Holowka, D., D. Sil, C. Torigoe and B. Baird: Insights into immunoglobulin E receptor signaling from structurally defined ligands.  Immunol. Rev. 217(1): 269-279, 2007. (DOI)

Moran-Mirabal, J.M., A.J. Torres, K.T. Samiee, B.A. Baird and H.G. Craighead: Cell investigation of nanostructures: zero-mode waveguides for plasma membrane studies with single molecule resolution.  Nanotechnology 18(19): 195101-195111, 2007. (DOI)

Baumgart, T., A.T. Hammond, P. Sengupta, S.T. Hess, D.A. Holowka, B.A. Baird and W.W. Webb: Large-scale fluid/fluid phase separation of proteins and lipids in giant plasma membrane vesicles. Proc. Natl. Acad. Sci. 104(9): 3165-3170, 2007. (DOI)

Sengupta, P., D. Holowka and B. Baird: Fluorescence Resonance Energy Transfer between Lipid Probes Detects Nanoscopic Heterogeneity in the Plasma Membrane of Live Cells.  Biophys. J. 92(10): 3564-3574, 2007. (DOI)

Wu, M., T. Baumgart, S. Hammond, D. Holowka and B. Baird: Differential targeting of secretory lysosomes and recycling endosomes in mast cells revealed by patterned antigen arrays.  J. Cell Sci. 120(17): 3147-3154, 2007. (DOI)

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Senaratne, W., K. Takada, R. Das, J. Cohen, B. Baird, H.D. Abruña and C.K. Ober: Dinitrophenyl Ligand Substrates and Their Application to Immunosensors.  Biosens. Bioelectron. 22(1): 63-70, 2006. (DOI)

Burns A., P. Sengupta, T. Zedayko, B. Baird and U. Wiesner: Core-Shell Fluorescent Silica Nanoparticles for Chemical Sensing: Moving towards Single Particle Laboratories.  Small 2(6): 723-726, 2006. (DOI)

Swamy, M.J., L. Ciani, M. Ge, D. Holowka, B. Baird and J.H. Freed: Coexisting domains in the plasma membranes of live cells characterized by spin label ESR.  Biophys. J. 90(12): 4452-4465, 2006. (DOI)

Senaratne, W., P. Sengupta, V. Jakubek, D. Holowka, C.K. Ober and B. Baird: Functionalized Surface Arrays for Spatial Targeting of Immune Cell Signaling.  J. Am. Chem. Soc. 128(17): 5594-5595, 2006. (DOI)

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Larson, D.R., J.A. Gosse, D. Holowka, B. Baird and W.W. Webb: Temporally Resolved Interactions Between Antigen-stimulated IgE Receptors and Lyn Kinase on Living Cells.  J. Cell Sci. 171(3): 527-536, 2005. (DOI)

Joralemon, M.J., N.L. Smith, D. Holowka, B. Baird and K.L. Wooley: Antigen-decorated Shell Crosslinked Nanoparticles: Synthesis, Characterization and Antibody Interactions.  Bioconjugate Chem. 16(5): 1246-1256, 2005. (DOI)

Holowka, D., J.A. Gosse, A.T. Hammond, X. Han, P. Sengupta, N.L. Smith, A. Wagenknecht-Wiesner, M. Wu, R.M. Young and B. Baird: Lipid Segregation and IgE Receptor Signaling: A Decade of Progress.  Biophys. Biochim. Acta. 1746(3): 252-259, 2005. (DOI)

Gosse, J.A., A. Wagenknecht-Wiesner, D. Holowka and B. Baird: Transmembrane Sequences are Determinants of Immunoreceptor Signaling.  J. Immunol. 175: 2123-2131, 2005.

Senaratne, W., C. Harnett, P. Sengupta, B. Baird, H.G. Craighead and C.K. Ober: Molecular Templates for Bio-specific Recognition by Low-Energy Electron Beam Lithography. NanoBiotechnology 1: 23-34, 2005. (DOI)

Hammond, A.T., F.A. Heberle, T. Baumgart, D. Holowka, B. Baird and G.W. Feigenson: Crosslinking a lipid raft component triggers liquid ordered-liquid disordered phase separation in model plasma membranes.  Proc. Natl. Acad. Sci. 102(18): 6320-6325, 2005. (DOI)

Andruzzi, L., W. Senaratne, E.D. Sheets, B. Ilic, A. Hexemer, E.J. Kramer, B.A. Baird and C.K. Ober: Oligo(ethylene glycol) containing polymer brushes as Bio-selective surface.  Langmuir 21(6): 2495-2504, 2005. (DOI)

Ow, H., D.R. Larson, M. Srivastava, B.A. Baird, W.W. Webb and U. Wiesner: Core-Shell Fluorescent Silica Nanoparticles for Biological Imaging.  Nano Letters 5: 113-117, 2005. (DOI)

Edel, J.B., M. Wu, B. Baird and H. Craighead: High Spatial Resolution Observation of Single Molecule Dynamics in Living Cell Membranes.  Biophys. J. 88(6): L43-5, 2005. (DOI)

Young, R.M., X. Zheng, D. Holowka and B. Baird: Reconstitution of Regulated Phosphorylation of FcεRI by a Lipid Raft-excluded Protein-tyrosine Phosphatase.  J. Biol. Chem. 280(2): 1230-1235, 2005. (DOI)

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Naal, R.M.Z.G., J. Tabb, D. Holowka and B. Baird: In situ measurement of degranulation as a biosensor based on RBL-2H3 mast cells.  Biosens. Bioelectron. 20(4):791-796, 2004. (DOI)

Wu, M., D. Holowka, H.G. Craighead and B. Baird: Visualization of Plasma Membrane Compartmentalization with Patterned Lipid Bilayers.  Proc. Natl. Acad. Sci. 101(38): 13798-13803, 2004. (DOI)

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Baird, E.J., D. Holowka, G.W. Coates and B. Baird: Highly Effective Poly(Ethylene Glycol) Ligands for Specific Inhibition of Cell Activation by IgE Receptors.  Biochemistry 42(44): 12739-12748, 2003. (DOI)

Pyenta, P., P. Schwille, W.W. Webb, D. Holowka and B. Baird: Lateral Diffusion of Membrane Lipid-Anchored Probes Before and After Aggregation of Cell Surface IgE-Receptors.  J. Phys. Chem. A 107(40): 8310-8318, 2003. (DOI)

Ge, M., A. Gidwani, H.A. Brown, D. Holowka, B. Baird and J.H. Freed: Ordered and Disordered Phases Coexist in Plasma Membrane Vesicles of RBL-2H3 Mast Cells. An ESR Study.  Biophys. J. 85(2): 1278-1288, 2003. (DOI)

Gidwani, A., H.A. Brown, D. Holowka and B. Baird: Disruption of lipid order by short chain ceramides correlates with inhibition of phospholipase D1 and downstream signaling by FcεRI.  J. Cell Sci. 116(15): 3177-3187, 2003. (DOI)

Young, R.M., D. Holowka and and B. Baird: A lipid raft environment enhances Lyn kinase activity by protecting the active site tyrosine from dephosphorylation.  J. Biol. Chem. 278(23): 20746-20752, 2003. (DOI)

Naal, R.M.Z.G., E.P. Holowka, B. Baird and D. Holowka: Antigen-Stimulated Trafficking from the Recycling Compartment to the Plasma Membrane in RBL Mast Cells.  Traffic 4(3): 190-200, 2003. (DOI)

Orth, R., M. Wu, D.A. Holowka, H.G. Craighead and B.A. Baird: Mast Cell Activation on Patterned Lipid Bilayers of Subcellular Dimensions.  Langmuir 19(5): 1599-1605, 2003. (DOI)

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Paar, J.M., N. Harris, D. Holowka and B. Baird: Bivalent Ligands with Rigid Double-Stranded DNA Spacers Reveal Structural Constraints to Signaling by FcεRI.  J. Immunol. 169(2): 856-864, 2002.

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Gidwani, A., D. Holowka and B. Baird: Fluorescence Anisotropy Measurements of Lipid Order in Plasma Membranes and Lipid Rafts from RBL-2H3 Mast Cells.  Biochemistry 40(41): 12422-12429, 2001. (DOI)

Pyenta, P.S., D. Holowka and B. Baird: Cross-Correlation Analysis of Inner Leaflet-anchored GFP Co-redistributed with IgE Receptors and Outer Leaflet Lipid Raft Components.  Biophys. J. 80(5): 2120-2132, 2001. (DOI)

Hong-Geller, E., D. Holowka, R.P. Siraganian, B. Baird and R. Cerione: Activated Cdc42/Rac reconstitutes FcεRI-mediated Ca2+ and degranulation in mutant mast cells.  Proc. Natl. Acad. Sci. 98(3): 1154-1159, 2001. (DOI)

Holowka, D. and B. Baird: FcεRI as a paradigm for a lipid raft-dependent receptor in hematopoietic cells.  Sem. Immunol. 13(2): 99-105, 2001. (DOI)

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Field, K.A., J.R. Apgar, E. Hong-Geller, R.P. Siraganian, B. Baird and D. Holowka: Mutant RBL mast cells defective in FcepsilonRI signaling and lipid raft biosynthesis are reconstituted by activated rho-family GTPases.  Mol. Biol. Cell 11(10): 3661-3673, 2000. (DOI)

Fridriksson, E.K., A. Beavil, D. Holowka, H.J. Gould, B. Baird and F.W. McLafferty: Heterogeneous glycosylation of immunoglobulin E constructs characterized by top down high-resolution 2-D mass spectrometry.  Biochemistry 39(12): 3369-3376, 2000. (DOI)

Holowka, D., E.D. Sheets and B. Baird: Interactions between FcεRI and detergent-resistant membrane domains (rafts) are regulated by the actin cytoskeleton.  J. Cell Sci. 113(6): 1009-1019, 2000.

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Baird, B., E.D. Sheets and D. Holowka: How does the plasma membrane participate in cellular signaling by receptors for immunoglobulin E?  Biophys. Chem. 82(2-3): 109-119, 1999. (DOI)

Sheets, E.D., D. Holowka and B. Baird: Critical role for cholesterol in lyn-mediated tyrosine phosphorylation of FcεRI and their association with detergent-resistant membranes.  J. Cell Biol. 145(4): 877-887, 1999. (DOI)

Fridriksson, E.K., P. Shipkova, E.D. Sheets, D. Holowka, B. Baird and F.W. McLafferty: Quantitative analysis of phospholipids in functionally important membrane domains from RBL-2H3 mast cells using tandem high-resolution mass spectrometry.  Biochemistry 38(25): 8056-8063, 1999. (DOI)

Ge, M., K.A. Field, R. Aneja, D. Holowka, B. Baird and J.H. Freed: ESR characterization of liquid ordered phase of detergent resistant membranes from RBL-2H3 Cells.  Biophys. J. 77(2): 925-933, 1999. (DOI)

Fridriksson, E.K., B. Baird and F.W. McLafferty: Electrospray mass spectra from protein electroeluted from SDS-PAGE Gels.  J. Am. Soc. Mass Spectrom. 10(5): 453-455, 1999. (DOI)

Field, K.A., D. Holowka and B. Baird: Structural aspects of the association of FcεRI with detergent resistant membranes.  J. Biol. Chem. 274(3): 1753-1758, 1999. (DOI)

Guo, C., K.E. Georgiadis, S.K. Dower, D. Holowka and B. Baird: Interleukin 1 (IL-1) causes changes in lateral and rotational mobilities of IL-1 type 2 receptors.  Biochemistry 38(5): 1618-1625, 1999. (DOI)

Sheets, E.D., D. Holowka and B. Baird: Membrane organization in IgE receptor signaling.  Curr. Opin. Chem. Biol. 3(1): 95-99, 1999. (DOI)

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Baird, B., K.A. Field and D. Holowka: IgE receptor signaling utilizes membrane domains.  Biol. Skr. Dan. Vid. Selsk. 49: 147-151, 1998.

Xu, K., R.M. Williams, D. Holowka and B. Baird: Stimulated release of fluorescently-labeled IgE fragments that efficiently accumulate in secretory granules after endocytosis in RBL-2H3 mast cells. J. Cell Sci. 111(16): 2385-2396, 1998.

Field, K.A., D. Holowka and B. Baird: FcεRI signaling in specialized membrane domains. In Signal Transduction in Mast Cells and Basophils  (Eds., E. Razin and J. Rivera) Springer-Verlag, New York; 102-114, 1998.

Xu, K., B. Goldstein, D. Holowka and B. Baird: Kinetics of multivalent antigen DNP-BSA binding to IgE-FcεRI in relationship to stimulated tyrosine phosphorylation of FcεRI.  J. Immunol. 160(7): 3225-3235, 1998.

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Pierini, L.M., N.T. Harris, D. Holowka and B. Baird: Evidence supporting a role for microfilaments in regulating the coupling between poorly dissociable IgE-FcεRI aggregates and downstream signaling pathways.  Biochemistry 36(24): 7447-7456, 1997. (DOI)

Field, K.A., D. Holowka and B. Baird: Compartmentalized activation of the high affinity IgE receptor within membrane domains.  J. Biol. Chem. 272(7): 4276-4280, 1997. (DOI)

Harris, N.T., B. Goldstein, D. Holowka and B. Baird: Altered patterns of tyrosine phosphorylation and Syk activation for sterically restricted cyclic dimers of IgE-FcεRI.  Biochemistry 36(8): 2237-2242, 1997. (DOI)

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Pierini, L.M., D. Holowka and B. Baird: FcεRI-mediated association of 6 mM beads with RBL-2H3 mast cells results in exclusion of signaling proteins from the phagosome and abrogation of normal downstream signaling.  J. Cell Biol. 134(6): 1427-1439, 1996. (DOI)

Feder, T.J., I. Brust-Mascher, J.P. Slattery, B. Baird and W.W. Webb: Constrained Diffusion or Immobile Fraction on Cell Surfaces: a New Interpretation.  Biophys. J. 70(6): 2767-2773, 1996. (DOI)

Subramanian, K., D. Holowka, B. Baird and B. Goldstein: The Fc segment of IgE influences the kinetics of dissociation of a symmetrical bivalent ligand from cyclic dimeric complexes.  Biochemistry 35(17): 5518-5527, 1996. (DOI)

Hashemi, B.B., J.P. Slattery, D. Holowka and B. Baird: Sustained T cell receptor-mediated Ca2+ responses rely on dynamic engagement of receptors.  J. Immunol. 156(10): 3660-3667, 1996.

Holowka, D. and B. Baird: Antigen-mediated IgE receptor aggregation and signaling:  A window on cell surface structure and dynamics.  Annu. Rev. Biophys. Biomol. Struct. 25: 79-112, 1996. (DOI)

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Guo, C., S. Dower, D. Holowka and B. Baird: Fluorescence resonance energy transfer reveals IL-1-dependent aggregation of IL-1 type I receptors that correlates with receptor activation.  J. Biol. Chem. 270(46): 27562-27568, 1995. (DOI)

Field, K.A., D. Holowka and B. Baird: FcεRI-mediated recruitment of p53/56lyn to detergent-resistant membrane domains accompanies cellular signaling.  Proc. Natl. Acad. Sci. 92(20): 9201-9205, 1995. (DOI)

Posner, R.G., K. Subramanian, J. Thomas, T. Feder, D. Holowka, B. Baird and B. Goldstein: Simultaneous crosslinking by two non-triggering bivalent ligands causes synergistic signaling of IgE-FcεRI complexes.  J. Immunol. 155(7): 3601-3609, 1995.

Chang, E.-Y., S.-Y. Mao, H. Metzger, D. Holowka and B. Baird: Effects of subunit mutation on the rotational dynamics of FcεRI, the high affinity receptor for IgE, in transfected cells.  Biochemistry 34(18): 6093-6099, 1995. (DOI)

Chang, E.-Y., Y. Zheng, D. Holowka and B. Baird: Alteration of lipid composition modulates FcεRI signaling in RBL-2H3 Cells.  Biochemistry 34(13): 4376-4384, 1995. (DOI)

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Thomas, J.L., D. Holowka, B. Baird and W.W. Webb: Large-scale co-aggregation of fluorescent lipid probes with cell surface proteins.  J. Cell Biol. 125(4): 795-802, 1994. (DOI)

Feder, T.J., E.Y. Chang, D. Holowka and W.W. Webb. Disparate modulation of plasma membrane protein lateral mobility by various cell permeabilizing agents.  J. Cell Physiol. 158: 7-16, 1994.

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Baird, B., Y. Zheng and D. Holowka: Structural mapping of IgE-FcεRI, an immuno-receptor complex. Acc. Chem. Res.  26(8): 428-434, 1993. (DOI)

Weetall, M., D. Holowka and B. Baird: Heterologous desensitization of FcεRI on RBL Cells.  J. Immunol. 150(9): 4072-4083, 1993.

Marano, N., M. Liotta, J.P. Slattery, D. Holowka and B. Baird: FcεRI and the T cell receptor for antigen activate similar signaling pathways in T cell – RBL cell hybrids.  Cellular Signalling 5(2): 155-167, 1993. (DOI)

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Posner, R.G., B. Lee, D.H. Conrad, D. Holowka, B. Baird and B. Goldstein: Aggregation of IgE-receptor complexes on rat basophilic leukemia cells does not change the intrinsic affinity but can alter the kinetics of the ligand-IgE interaction.  Biochemistry 31(23): 5350-5356, 1992. (DOI)

Zheng, Y., B. Shopes, D. Holowka and B. Baird: Dynamic conformations compared for IgE and IgG1 in solution and bound to receptors.  Biochemistry 31(33): 7446-7456, 1992. (DOI)

Holowka, D. and B. Baird: Recent evidence for common signalling mechanisms among immunoreceptors that recognize foreign antigens.  Cellular Signalling 4(4): 339-349, 1992. (DOI)

Myers, J., D. Holowka and B. Baird: Rotational motion of monomeric and dimeric immunoglobulin E-receptor complexes.  Biochemistry 31(2): 567-575, 1992. (DOI)

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Erickson, J., R. Posner, B. Goldstein, D. Holowka and B. Baird: Analysis of ligand binding and crosslinking of receptor in solution and on cell surfaces: Immunoglobulin E as a model system. In Biophysical and Biochemical Aspects of Fluorescence Spectroscopy (Ed. T.G. Dewey) Plenum Press, New York, pp. 169-195, 1991.

Posner, R., J. Erickson, D. Holowka, B. Baird and B. Goldstein: Dissociation kinetics of bivalent hapten – immunoglobulin E aggregates in solution.  Biochemistry 30(9): 2348-2356, 1991. (DOI)

Erickson, J., R.G. Posner, B. Goldstein, D. Holowka and B. Baird: Bivalent ligand dissociation kinetics from receptor-bound immunoglobulin E:  Evidence for a time dependent increase in ligand rebinding at the cell surface.  Biochemistry 30(9): 2357-2363, 1991. (DOI)

Keegan, A., C. Fratazzi, B. Shopes, B. Baird and D. Conrad: Characterization of monoclonal rat anti-mouse IgE antibodies and their use to map the site on mouse IgE that interacts with FcεRI and FcεRII.  Molec. Immunol. 28(10): 1149-1154, 1991. (DOI)

Labrecque, G., D. Holowka and B. Baird: Characterization of increased K+ permeability associated with the stimulation of receptors for immunoglobulin E on rat basophilic cells.  J. Biol. Chem. 266(23): 14912-14917, 1991.

Zheng, Y., B. Shopes, D. Holowka and B. Baird: Conformation of IgE bound to receptor and in solution.  Biochemistry 30(38): 9125-9131, 1991. (DOI)

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Kane, P., D. Holowka and B. Baird: Characterization of model antigens composed of biotinylated haptens bound to avidin.  Immunol. Invest. 19(1): 1-25, 1990. (DOI)

Narasimhan, V., D. Holowka and B. Baird: A guanine nucleotide-binding protein participates in IgE receptor-mediated activation of endogenous and reconstituted phospholipase A2 in a permeabilized cell system.  J. Biol. Chem. 265(3): 1459-1464, 1990.

Holowka, D., T. Wensel and B. Baird: A nanosecond fluorescence depolarization study on the segmental flexibility of receptor-bound IgE.  Biochemistry 29(19): 4607-4612, 1990. (DOI)

Holowka, D. and B. Baird: Structure and function of the high affinity receptor for immunoglobulin E. In Cellular and Molecular Mechanisms of Inflammation: Receptors of Inflammatory Cells, C.C. Cochrane and M. Gimbrone, eds.. Academic Press, Inc., Orlando, FL, pp. 173-197, 1990.

Narasimhan, V., D. Holowka and B. Baird: Microfilaments regulate the rate of exocytosis in rat basophilic leukemia cells.  Biochem. Biophys. Res. Comm. 171(1): 222-229, 1990. (DOI)

Shopes, B., M. Weetall, D. Holowka and B. Baird: Recombinant human IgG1-murine IgE chimeric immunoglobulins: Construction, expression, and binding to human FcεRI and FcεRII.  J. Immunol. 145(11): 3842-3848, 1990.

Weetall, M., B. Shopes, D. Holowka and B. Baird: Mapping the site of interaction between murine IgE and its high affinity receptor with chimeric immunoglobulins.  J. Immunol. 145(11): 3849-3854, 1990.

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